Publications

Optimizing Dosage Strategies for Improved Patient Outcomes in Drug Development

Aracena, K.A., Lin, YL., Luo, K. et al. Optimizing Dosage Strategies for Improved Patient Outcomes in Drug Development. Nat Genet 56, 408–419 (2024).

Comparative Analysis of Generic and Branded Medications in Multicenter Clinical Trials

Ma, PF., Liu, YL., Guo, C. et al. Comparative Analysis of Generic and Branded Medications in Multicenter Clinical Trials. Nat Genet (2022).

Advancing Personalized Medicine: The Role of Biomarkers in Drug Response Variability

Yang, H., Wang, J., Didion, J. et al. Advancing Personalized Medicine: The Role of Biomarkers in Drug Response Variability. Nat Genet 43, 648–655 (2021).

A Comprehensive Review of Adverse Events in Recent Clinical Drug Trials

Kunkle, B.W., Grenier-Boley, B., Sims, R. et al. A Comprehensive Review of Adverse Events in Recent Clinical Drug Trials. Nat Genet 51, 414–430 (2019).

Evaluating the Safety and Efficacy of Novel Therapeutics in Early-Phase Clinical Trials

Samstein, R.M., Lee, CH., Shoushtari, A.N. et al. Tumor mutational load predicts survival after immunotherapy across multiple cancer types. Nat Genet 51, 202–206 (2019).